human SLC17A8 shRNA silencing AAV

Cat. No: shAAV-223152

Availability: 6-8 weeks

Name: AAV-h-SLC17A8-shRNA

This is an AAV expressing shRNA for silencing of Human SLC17A8.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SLC17A8
Gene Name: solute carrier family 17 member 8
Gene ID: 246213
Gene Synonyms: DFNA25; VGLUT3
ORF Size: 1620 bp
RefSeq#: NM_139319
Gene Description: SLC17A8 encodes a vesicular glutamate transporter. The encoded protein transports the neurotransmitter glutamate into synaptic vesicles before it is released into the synaptic cleft. Mutations in this gene are the cause of autosomal-dominant nonsyndromic type 25 deafness. Alternate splicing results in multiple transcript variants.
UniGene ID: Hs.116871
HGNC ID: HGNC:20151