human SIVA1 shRNA silencing AAV

Cat. No: shAAV-223030

Availability: 6-8 weeks

Name: AAV-h-SIVA1-shRNA

This is an AAV expressing shRNA for silencing of Human SIVA1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SIVA1
Gene Name: SIVA1 apoptosis inducing factor
Gene ID: 10572
Gene Synonyms: CD27BP; SIVA; Siva-1; Siva-2
ORF Size: 333 bp
RefSeq#: NM_006427
Gene Description: SIVA1 encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. The CD27 antigen cytoplasmic tail binds to the N-terminus of this protein. Two alternatively spliced transcript variants encoding distinct proteins have been described.
UniGene ID: Hs.112058
HGNC ID: HGNC:17712