human SIL1 shRNA silencing AAV

Cat. No: shAAV-223001

Availability: 4-5 weeks

Name: AAV-h-SIL1-shRNA

This is an AAV expressing shRNA for silencing of Human SIL1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SIL1
Gene Name: SIL1 nucleotide exchange factor
Gene ID: 64374
Gene Synonyms: BAP; MSS; ULG5
ORF Size: 1386 bp
RefSeq#: NM_022464
Gene Description: SIL1 encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized.
UniGene ID: Hs.483521
HGNC ID: HGNC:24624