human SIGMAR1 shRNA silencing AAV

Cat. No: shAAV-222997

Availability: 4-5 weeks

Name: AAV-h-SIGMAR1-shRNA

This is an AAV expressing shRNA for silencing of Human SIGMAR1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SIGMAR1
Gene Name: sigma non-opioid intracellular receptor 1
Gene ID: 10280
Gene Synonyms: ALS16; DSMA2; hSigmaR1; OPRS1; SIG-1R; sigma1R; SR-BP; SR-BP1; SRBP
ORF Size: 672 bp
RefSeq#: NM_005866
Gene Description: SIGMAR1 encodes a receptor protein that interacts with a variety of psychotomimetic drugs, including cocaine and amphetamines. The receptor is believed to play an important role in the cellular functions of various tissues associated with the endocrine, immune, and nervous systems. As indicated by its previous name, opioid receptor sigma 1 (OPRS1), the product of this gene was erroneously thought to function as an opioid receptor; it is now thought to be a non-opioid receptor. Alternative splicing of this gene results in transcript variants encoding distinct isoforms.
UniGene ID: Hs.522087
HGNC ID: HGNC:8157