human SHBG shRNA silencing AAV

Cat. No: shAAV-222927

Availability: 6-8 weeks

Name: AAV-h-SHBG-shRNA

This is an AAV expressing shRNA for silencing of Human SHBG.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SHBG
Gene Name: sex hormone binding globulin
Gene ID: 6462
Gene Synonyms: ABP; SBP; TEBG
ORF Size: 1209 bp
RefSeq#: NM_001040
Gene Description: SHBG encodes a steroid binding protein that was first described as a plasma protein secreted by the liver but is now thought to participate in the regulation of steroid responses. The encoded protein binds each steroid molecule as a dimer formed from identical or nearly identical monomers. The use of alternate promoters and alternatively spliced transcripts have been described. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.632235
HGNC ID: HGNC:10839