human SGPP1 shRNA silencing AAV

Cat. No: shAAV-222866

Availability: 4-5 weeks

Name: AAV-h-SGPP1-shRNA

This is an AAV expressing shRNA for silencing of Human SGPP1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SGPP1
Gene Name: sphingosine-1-phosphate phosphatase 1
Gene ID: 81537
Gene Synonyms: SPPase1
ORF Size: 1326 bp
RefSeq#: NM_030791
Gene Description: Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 (PubMed 10859351); Le Stunff et al., 2007 (PubMed 17895250)).(supplied by OMIM, Jun 2009)
UniGene ID: Hs.24678
HGNC ID: HGNC:17720