human SF3A2 shRNA silencing AAV

Cat. No: shAAV-222757

Availability: 4-5 weeks

Name: AAV-h-SF3A2-shRNA

This is an AAV expressing shRNA for silencing of Human SF3A2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SF3A2
Gene Name: splicing factor 3a subunit 2
Gene ID: 8175
Gene Synonyms: PRP11; PRPF11; SAP62; SF3a66
ORF Size: 1395 bp
RefSeq#: NM_007165
Gene Description: SF3A2 encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein.
UniGene ID: Hs.115232
HGNC ID: HGNC:10766