human SERPINB9 shRNA silencing AAV

Cat. No: shAAV-222701

Availability: 4-5 weeks

Name: AAV-h-SERPINB9-shRNA

This is an AAV expressing shRNA for silencing of Human SERPINB9.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SERPINB9
Gene Name: serpin family B member 9
Gene ID: 5272
Gene Synonyms: CAP-3; CAP3; PI-9; PI9
ORF Size: 1131 bp
RefSeq#: NM_004155
Gene Description: SERPINB9 encodes a member of the serine protease inhibitor family which are also known as serpins. The encoded protein belongs to a subfamily of intracellular serpins. This protein inhibits the activity of the effector molecule granzyme B. Overexpression of this protein may prevent cytotoxic T-lymphocytes from eliminating certain tumor cells. A pseudogene of this gene is found on chromosome 6.
UniGene ID: Hs.104879
HGNC ID: HGNC:8955