human SEPT6 shRNA silencing AAV

Cat. No: shAAV-222610

Availability: 4-5 weeks

Name: AAV-h-SEPT6-shRNA

This is an AAV expressing shRNA for silencing of Human SEPT6.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SEPT6
Gene Name: septin 6
Gene ID: 23157
Gene Synonyms: SEP2; SEPT2
ORF Size: 1305 bp
RefSeq#: NM_015129
Gene Description: 6-Sep is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. 6-Sep encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.
UniGene ID: Hs.496666
HGNC ID: HGNC:15848