human SCO2 shRNA silencing AAV

Cat. No: shAAV-222384

Availability: 4-5 weeks

Name: AAV-h-SCO2-shRNA

This is an AAV expressing shRNA for silencing of Human SCO2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SCO2
Gene Name: SCO2, cytochrome c oxidase assembly protein
Gene ID: 9997
Gene Synonyms: CEMCOX1; MYP6; SCO1L
ORF Size: 801 bp
RefSeq#: NM_005138
Gene Description: Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors; this gene encodes one of the COX asembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy.
UniGene ID: Hs.718545
HGNC ID: HGNC:10604