human SAT1 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-222268
Availability:
4-5 weeks
Name:
AAV-h-SAT1-shRNA
This is an AAV expressing shRNA for silencing of Human SAT1.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- SAT1
- Gene Name
- spermidine/spermine N1-acetyltransferase 1
- Gene ID
- 6303
- Gene Synonyms
- DC21; KFSD; KFSDX; SAT; SSAT; SSAT-1
- ORF Size
- 516 bp
- RefSeq#
- NM_002970
- Gene Description
- SAT1 belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.
- UniGene ID
- Hs.28491
- HGNC ID
- HGNC:10540
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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