human SAR1B shRNA silencing AAV

Cat. No: shAAV-222250

Availability: 4-5 weeks

Name: AAV-h-SAR1B-shRNA

This is an AAV expressing shRNA for silencing of Human SAR1B.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: SAR1B
Gene Name: secretion associated Ras related GTPase 1B
Gene ID: 51128
Gene Synonyms: ANDD; CMRD; GTBPB; SARA2
ORF Size: 597 bp
RefSeq#: NM_016103
Gene Description: SAR1B is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.
UniGene ID: Hs.432984
HGNC ID: HGNC:10535