human RPS6KB2 shRNA silencing AAV

Cat. No: shAAV-221944

Availability: 4-5 weeks

Name: AAV-h-RPS6KB2-shRNA

This is an AAV expressing shRNA for silencing of Human RPS6KB2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RPS6KB2
Gene Name: ribosomal protein S6 kinase B2
Gene ID: 6199
Gene Synonyms: KLS; p70(S6K)-beta; P70-beta; P70-beta-1; P70-beta-2; p70S6Kb; S6K-beta2; S6K2; SRK; STK14B
ORF Size: 1449 bp
RefSeq#: NM_003952
Gene Description: RPS6KB2 encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.
UniGene ID: Hs.534345
HGNC ID: HGNC:10437