human RLIM shRNA silencing AAV

Cat. No: shAAV-221273

Availability: 4-5 weeks

Name: AAV-h-RLIM-shRNA

This is an AAV expressing shRNA for silencing of Human RLIM.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RLIM
Gene Name: ring finger protein, LIM domain interacting
Gene ID: 51132
Gene Synonyms: MRX61; NY-REN-43; RNF12
ORF Size: 1875 bp
RefSeq#: NM_016120
Gene Description: RLIM is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified.
UniGene ID: Hs.653288
HGNC ID: HGNC:13429