human RERE shRNA silencing AAV

Cat. No: shAAV-221011

Availability: 4-5 weeks

Name: AAV-h-RERE-shRNA

This is an AAV expressing shRNA for silencing of Human RERE.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RERE
Gene Name: arginine-glutamic acid dipeptide repeats
Gene ID: 473
Gene Synonyms: ARG; ARP; ATN1L; DNB1; NEDBEH
ORF Size: 4701 bp
RefSeq#: NM_012102
Gene Description: RERE encodes a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in mouse associates with histone deacetylase and is thought to function as a transcriptional co-repressor during embryonic development. Multiple transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.463041
HGNC ID: HGNC:9965