human RELT shRNA silencing AAV

Cat. No: shAAV-221000

Availability: 6-8 weeks

Name: AAV-h-RELT-shRNA

This is an AAV expressing shRNA for silencing of Human RELT.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RELT
Gene Name: RELT tumor necrosis factor receptor
Gene ID: 84957
Gene Synonyms: TNFRSF19L; TRLT
ORF Size: 1293 bp
RefSeq#: NM_032871
Gene Description: RELT is a member of the TNF-receptor superfamily. This receptor is especially abundant in hematologic tissues. It has been shown to activate the NF-kappaB pathway and selectively bind TNF receptor-associated factor 1 (TRAF1). This receptor is capable of stimulating T-cell proliferation in the presence of CD3 signaling, which suggests its regulatory role in immune response. Two alternatively spliced transcript variants of this gene encoding the same protein have been reported.
UniGene ID: Hs.533720
HGNC ID: HGNC:13764