human RELA shRNA silencing AAV

Cat. No: shAAV-220994

Availability: 4-5 weeks

Name: AAV-h-RELA-shRNA

This is an AAV expressing shRNA for silencing of Human RELA.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RELA
Gene Name: RELA proto-oncogene, NF-kB subunit
Gene ID: 5970
Gene Synonyms: NFKB3; p65
ORF Size: 1647 bp
RefSeq#: NM_021975
Gene Description: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.502875
HGNC ID: HGNC:9955