human RBMY1B shRNA silencing AAV

Cat. No: shAAV-220906

Availability: 6-8 weeks

Name: AAV-h-RBMY1B-shRNA

This is an AAV expressing shRNA for silencing of Human RBMY1B.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RBMY1B
Gene Name: RNA binding motif protein, Y-linked, family 1, member B
Gene ID: 378948
ORF Size: 1491 bp
RefSeq#: NM_001006121
Gene Description: RBMY1B encodes a protein containing an RNA-binding motif in the N-terminus and four SRGY (serine, arginine, glycine, tyrosine) boxes in the C-terminus. Multiple copies of this gene are found in the AZFb azoospermia factor region of chromosome Y and the encoded protein is thought to be involved in spermatogenesis. Most copies of this locus are pseudogenes, although six highly similar copies have full-length ORFs and are considered functional. Four functional copies of this gene are found within inverted repeat IR2; two functional copies of this gene are found in palindrome P3, along with two copies of PTPN13-like, Y-linked.
UniGene ID: Hs.536001
HGNC ID: HGNC:23914