human RARS2 shRNA silencing AAV

Product Info

Knockdown

>80% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Recombinant AAV

AAV-ITR

AAV2

AAV Serotype

Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

PBS/5% Glycerol

Gene Details

Species

Human

Gene Symbol

RARS2

Gene Name

arginyl-tRNA synthetase 2, mitochondrial

Gene ID

57038

Gene Synonyms

ArgRS; DALRD2; PCH6; PRO1992; RARSL

ORF Size

1737 bp

RefSeq#

NM_020320

Gene Description

RARS2 is an arginyl-tRNA synthetase that is found in the mitochondrial matrix. Defects in this gene are a cause of pontocerebellar hypoplasia type 6 (PCH6).

UniGene ID

Hs.485910

HGNC ID

HGNC:21406