human RARA shRNA silencing AAV

Cat. No: shAAV-220747

Availability: 4-5 weeks

Name: AAV-h-RARA-shRNA

This is an AAV expressing shRNA for silencing of Human RARA.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RARA
Gene Name: retinoic acid receptor alpha
Gene ID: 5914
Gene Synonyms: NR1B1; RAR
ORF Size: 1389 bp
RefSeq#: NM_000964
Gene Description: RARA represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. RARA has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.
UniGene ID: Hs.654583
HGNC ID: HGNC:9864