human RALBP1 shRNA silencing AAV

Cat. No: shAAV-220682

Availability: 4-5 weeks

Name: AAV-h-RALBP1-shRNA

This is an AAV expressing shRNA for silencing of Human RALBP1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RALBP1
Gene Name: ralA binding protein 1
Gene ID: 10928
Gene Synonyms: RIP1; RLIP1; RLIP76
ORF Size: 1968 bp
RefSeq#: NM_006788
Gene Description: RALBP1 plays a role in receptor-mediated endocytosis and is a downstream effector of the small GTP-binding protein RAL (see RALA; MIM 179550). Small G proteins, such as RAL, have GDP-bound inactive and GTP-bound active forms, which shift from the inactive to the active state through the action of RALGDS (MIM 601619), which in turn is activated by RAS (see HRAS; MIM 190020) (summary by Feig, 2003 (PubMed 12888294)).(supplied by OMIM, Nov 2010)
UniGene ID: Hs.528993
HGNC ID: HGNC:9841