human RAD54L shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-220652
Availability:
4-5 weeks
Name:
AAV-h-RAD54L-shRNA
This is an AAV expressing shRNA for silencing of Human RAD54L.
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Product Info
- Knockdown
- >70% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- RAD54L
- Gene Name
- RAD54-like (S. cerevisiae)
- Gene ID
- 8438
- Gene Synonyms
- hHR54; HR54; hRAD54; RAD54A
- ORF Size
- 2244 bp
- RefSeq#
- NM_003579
- Gene Description
- RAD54L belongs to the DEAD-like helicase superfamily, and shares similarity with Saccharomyces cerevisiae Rad54, a protein known to be involved in the homologous recombination and repair of DNA. This protein has been shown to play a role in homologous recombination related repair of DNA double-strand breaks. The binding of this protein to double-strand DNA induces a DNA topological change, which is thought to facilitate homologous DNA paring, and stimulate DNA recombination. Alternative splicing results in multiple transcript variants encoding the same protein.
- UniGene ID
- Hs.642042
- HGNC ID
- HGNC:9826
Related Products
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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