human RAD21 shRNA silencing AAV

Cat. No: shAAV-220636

Availability: 4-5 weeks

Name: AAV-h-RAD21-shRNA

This is an AAV expressing shRNA for silencing of Human RAD21.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: RAD21
Gene Name: RAD21 cohesin complex component
Gene ID: 5885
Gene Synonyms: CDLS4; hHR21; HR21; HRAD21; MCD1; NXP1; SCC1
ORF Size: 1896 bp
RefSeq#: NM_006265
Gene Description: RAD21 is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells.
UniGene ID: Hs.81848
HGNC ID: HGNC:9811