human PTGS1 shRNA silencing AAV

Cat. No: shAAV-220256

Availability: 4-5 weeks

Name: AAV-h-PTGS1-shRNA

This is an AAV expressing shRNA for silencing of Human PTGS1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PTGS1
Gene Name: prostaglandin-endoperoxide synthase 1
Gene ID: 5742
Gene Synonyms: COX1; COX3; PCOX1; PES-1; PGG/HS; PGHS-1; PGHS1; PHS1; PTGHS
ORF Size: 1800 bp
RefSeq#: NM_000962
Gene Description: This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.201978
HGNC ID: HGNC:9604