human PSRC1 shRNA silencing AAV

Cat. No: shAAV-220199

Availability: 4-5 weeks

Name: AAV-h-PSRC1-shRNA

This is an AAV expressing shRNA for silencing of Human PSRC1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PSRC1
Gene Name: proline and serine rich coiled-coil 1
Gene ID: 84722
Gene Synonyms: DDA3; FP3214
ORF Size: 1092 bp
RefSeq#: NM_032636
Gene Description: PSRC1 encodes a proline-rich protein. Studies of this gene and the related mouse gene suggest that this gene is regulated by p53 and may participate in p53-mediated growth suppression. The encoded protein may function as a microtubule destabilizing protein that controls spindle dynamics and mitotic progression by recruiting and regulating microtubule depolymerases. At least one genetic variation in this gene has been associated with decreased serum levels of low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding different isoforms have been described.
UniGene ID: Hs.405925
HGNC ID: HGNC:24472