human PRSS8 shRNA silencing AAV

Cat. No: shAAV-220035

Availability: 6-8 weeks

Name: AAV-h-PRSS8-shRNA

This is an AAV expressing shRNA for silencing of Human PRSS8.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PRSS8
Gene Name: protease, serine 8
Gene ID: 5652
Gene Synonyms: CAP1; PROSTASIN
ORF Size: 1032 bp
RefSeq#: NM_002773
Gene Description: PRSS8 encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. The proprotein is cleaved to produce a light chain and a heavy chain which are associated by a disulfide bond. It is active on peptide linkages involving the carboxyl group of lysine or arginine.
UniGene ID: Hs.75799
HGNC ID: HGNC:9491