human PRSS7 shRNA silencing AAV

Cat. No: shAAV-220034

Availability: 6-8 weeks

Name: AAV-h-PRSS7-shRNA

This is an AAV expressing shRNA for silencing of Human TMPRSS15.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: TMPRSS15
Gene Name: transmembrane protease, serine 15
Gene ID: 5651
Gene Synonyms: ENTK; PRSS7
ORF Size: 3060 bp
RefSeq#: NM_002772
Gene Description: TMPRSS15 encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive.
UniGene ID: Hs.149473
HGNC ID: HGNC:9490