human PROK1 shRNA silencing AAV

Cat. No: shAAV-219927

Availability: 6-8 weeks

Name: AAV-h-PROK1-shRNA

This is an AAV expressing shRNA for silencing of Human PROK1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PROK1
Gene Name: prokineticin 1
Gene ID: 84432
Gene Synonyms: EGVEGF; PK1; PRK1
ORF Size: 318 bp
RefSeq#: NM_032414
Gene Description: PROK1 induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner.
UniGene ID: Hs.514793
HGNC ID: HGNC:18454