human PRDX4 shRNA silencing AAV

Cat. No: shAAV-219780

Availability: 4-5 weeks

Name: AAV-h-PRDX4-shRNA

This is an AAV expressing shRNA for silencing of Human PRDX4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PRDX4
Gene Name: peroxiredoxin 4
Gene ID: 10549
Gene Synonyms: AOE37-2; AOE372; HEL-S-97n; PRX-4
ORF Size: 816 bp
RefSeq#: NM_006406
Gene Description: PRDX4 is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB.
UniGene ID: Hs.83383
HGNC ID: HGNC:17169