human PQBP1 shRNA silencing AAV

Cat. No: shAAV-219702

Availability: 4-5 weeks

Name: AAV-h-PQBP1-shRNA

This is an AAV expressing shRNA for silencing of Human PQBP1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PQBP1
Gene Name: polyglutamine binding protein 1
Gene ID: 10084
Gene Synonyms: MRX2; MRX55; MRXS3; MRXS8; NPW38; RENS1; SHS
ORF Size: 798 bp
RefSeq#: NM_005710
Gene Description: PQBP1 encodes a nuclear polyglutamine-binding protein that is involved with transcription activation. The encoded protein contains a WW domain. Mutations in this gene have been found in patients with Renpenning syndrome 1 and other syndromes with X-linked mental retardation. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
UniGene ID: Hs.534384
HGNC ID: HGNC:9330