human PPP4R1 shRNA silencing AAV

Cat. No: shAAV-219682

Availability: 4-5 weeks

Name: AAV-h-PPP4R1-shRNA

This is an AAV expressing shRNA for silencing of Human PPP4R1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PPP4R1
Gene Name: protein phosphatase 4 regulatory subunit 1
Gene ID: 9989
Gene Synonyms: MEG1; PP4(Rmeg); PP4R1
ORF Size: 2802 bp
RefSeq#: NM_005134
Gene Description: PPP4R1 encodes one of several alternate regulatory subunits of serine/threonine protein phosphatase 4 (PP4). The protein features multiple HEAT repeats. This protein forms a complex with PP4RC. This complex may have a distinct role from other PP4 complexes, including regulation of HDAC3 (Zhang et al., PMID: 15805470). There is also a transcribed pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants.
UniGene ID: Hs.464595
HGNC ID: HGNC:9320