human PON1 shRNA silencing AAV

Cat. No: shAAV-219442

Availability: 6-8 weeks

Name: AAV-h-PON1-shRNA

This is an AAV expressing shRNA for silencing of Human PON1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PON1
Gene Name: paraoxonase 1
Gene ID: 5444
Gene Synonyms: ESA; MVCD5; PON
ORF Size: 1068 bp
RefSeq#: NM_000446
Gene Description: The enzyme encoded by this gene is an arylesterase that mainly hydrolyzes paroxon to produce p-nitrophenol. Paroxon is an organophosphorus anticholinesterase compound that is produced in vivo by oxidation of the insecticide parathion. Polymorphisms in this gene are a risk factor in coronary artery disease. The gene is found in a cluster of three related paraoxonase genes at 7q21.3.
UniGene ID: Hs.370995
HGNC ID: HGNC:9204