human POMGNT1 shRNA silencing AAV

Cat. No: shAAV-219434

Availability: 4-5 weeks

Name: AAV-h-POMGNT1-shRNA

This is an AAV expressing shRNA for silencing of Human POMGNT1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: POMGNT1
Gene Name: protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
Gene ID: 55624
Gene Synonyms: GnT I.2; gnT-I.2; GNTI.2; LGMD2O; MEB; MGAT1.2; RP76
ORF Size: 1983 bp
RefSeq#: NM_017739
Gene Description: POMGNT1 is a type II transmembrane protein that resides in the golgi. It participates in O-mannosyl glycosylation, and is specific for alpha linked terminal mannose. Mutations in this gene are associated with muscle-eye-brain (MEB) disease. Alternatively spliced transcript variants have been found for this gene.
UniGene ID: Hs.525134
HGNC ID: HGNC:19139