human POLL shRNA silencing AAV

Cat. No: shAAV-219371

Availability: 6-8 weeks

Name: AAV-h-POLL-shRNA

This is an AAV expressing shRNA for silencing of Human POLL.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: POLL
Gene Name: DNA polymerase lambda
Gene ID: 27343
Gene Synonyms: BETAN; POLKAPPA
ORF Size: 903 bp
RefSeq#: NM_013274
Gene Description: POLL encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3'-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non-homologous end joining and other DNA repair processes. Alternatively spliced transcript variants have been described.
UniGene ID: Hs.523230
HGNC ID: HGNC:9184