human PNMA3 shRNA silencing AAV

Cat. No: shAAV-219298

Availability: 6-8 weeks

Name: AAV-h-PNMA3-shRNA

This is an AAV expressing shRNA for silencing of Human PNMA3.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PNMA3
Gene Name: paraneoplastic Ma antigen 3
Gene ID: 29944
Gene Synonyms: MA3; MA5
ORF Size: 1392 bp
RefSeq#: NM_013364
Gene Description: PNMA3 is a member of the paraneoplastic antigen MA (PNMA) gene family, whose protein products share homology with retroviral Gag proteins. They are highly expressed in the brain and also in a range of tumors associated with serious neurological phenotypes. PMID:16407312 reports the presence of a functional -1 ribosomal frameshift signal (consisting of a heptanucleotide shift motif followed 3' by a pseudoknot structure) in this gene, however, the frame-shifted product has not been characterized.
UniGene ID: Hs.449627
HGNC ID: HGNC:18742