human PKNOX2 shRNA silencing AAV

Cat. No: shAAV-219044

Availability: 4-5 weeks

Name: AAV-h-PKNOX2-shRNA

This is an AAV expressing shRNA for silencing of Human PKNOX2.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PKNOX2
Gene Name: PBX/knotted 1 homeobox 2
Gene ID: 63876
Gene Synonyms: PREP2
ORF Size: 1416 bp
RefSeq#: NM_022062
Gene Description: Homeodomain proteins are sequence-specific transcription factors that share a highly conserved DNA-binding domain and play fundamental roles in cell proliferation, differentiation, and death. PKNOX2 belongs to the TALE (3-amino acid loop extension) class of homeodomain proteins characterized by a 3-amino acid extension between alpha helices 1 and 2 within the homeodomain (Imoto et al., 2001 (PubMed 11549286)).(supplied by OMIM, Oct 2009)
UniGene ID: Hs.278564
HGNC ID: HGNC:16714