human PIWIL1 shRNA silencing AAV

Cat. No: shAAV-219010

Availability: 6-8 weeks

Name: AAV-h-PIWIL1-shRNA

This is an AAV expressing shRNA for silencing of Human PIWIL1.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PIWIL1
Gene Name: piwi like RNA-mediated gene silencing 1
Gene ID: 9271
Gene Synonyms: CT80.1; HIWI; MIWI; PIWI
ORF Size: 2586 bp
RefSeq#: NM_004764
Gene Description: PIWIL1 encodes a member of the PIWI subfamily of Argonaute proteins, evolutionarily conserved proteins containing both PAZ and Piwi motifs that play important roles in stem cell self-renewal, RNA silencing, and translational regulation in diverse organisms. The encoded protein may play a role as an intrinsic regulator of the self-renewal capacity of germline and hematopoietic stem cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
UniGene ID: Hs.405659
HGNC ID: HGNC:9007