human PISD shRNA silencing AAV

Cat. No: shAAV-218990

Availability: 6-8 weeks

Name: AAV-h-PISD-shRNA

This is an AAV expressing shRNA for silencing of Human PISD.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PISD
Gene Name: phosphatidylserine decarboxylase
Gene ID: 23761
Gene Synonyms: DJ858B16; dJ858B16.2; PSD; PSDC; PSSC
ORF Size: 1128 bp
RefSeq#: NM_014338
Gene Description: Phosphatidylserine decarboxylases (PSDs; EC 4.1.1.65) catalyze the formation of phosphatidylethanolamine (PE) by decarboxylation of phosphatidylserine (PS). Type I PSDs, such as PISD, are targeted to the inner mitochondrial membrane by an N-terminal targeting sequence. PISD also contains a conserved LGST motif that functions as an autocatalytic cleavage site where the proenzyme is split into mature alpha and beta subunits (Schuiki and Daum, 2009 (PubMed 19165886)).(supplied by OMIM, Jul 2010)
UniGene ID: Hs.420559
HGNC ID: HGNC:8999