human PIM3 shRNA silencing AAV

Cat. No: shAAV-218971

Availability: 6-8 weeks

Name: AAV-h-PIM3-shRNA

This is an AAV expressing shRNA for silencing of Human PIM3.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PIM3
Gene Name: Pim-3 proto-oncogene, serine/threonine kinase
Gene ID: 415116
Gene Synonyms: pim-3
ORF Size: 981 bp
RefSeq#: NM_001001852
Gene Description: PIM3 belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is overexpressed in hematological and epithelial tumors and is associated with MYC coexpression. It plays a role in the regulation of signal transduction cascades, contributing to both cell proliferation and survival, and provides a selective advantage in tumorigenesis.
UniGene ID: Hs.530381
HGNC ID: HGNC:19310