human PICK1 shRNA silencing AAV

Cat. No: shAAV-218898

Availability: 4-5 weeks

Name: AAV-h-PICK1-shRNA

This is an AAV expressing shRNA for silencing of Human PICK1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PICK1
Gene Name: protein interacting with PRKCA 1
Gene ID: 9463
Gene Synonyms: PICK; PRKCABP
ORF Size: 1248 bp
RefSeq#: NM_012407
Gene Description: PICK1 contains a PDZ domain, through which it interacts with protein kinase C, alpha (PRKCA). This protein may function as an adaptor that binds to and organizes the subcellular localization of a variety of membrane proteins. It has been shown to interact with multiple glutamate receptor subtypes, monoamine plasma membrane transporters, as well as non-voltage gated sodium channels, and may target PRKCA to these membrane proteins and thus regulate their distribution and function. This protein has also been found to act as an anchoring protein that specifically targets PRKCA to mitochondria in a ligand-specific manner. Three transcript variants encoding the same protein have been found for this gene.
UniGene ID: Hs.180871
HGNC ID: HGNC:9394