human PGM1 shRNA silencing AAV

Cat. No: shAAV-218759

Availability: 4-5 weeks

Name: AAV-h-PGM1-shRNA

This is an AAV expressing shRNA for silencing of Human PGM1.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PGM1
Gene Name: phosphoglucomutase 1
Gene ID: 5236
Gene Synonyms: CDG1T; GSD14
ORF Size: 1689 bp
RefSeq#: NM_002633
Gene Description: PGM1 is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.
UniGene ID: Hs.1869
HGNC ID: HGNC:8905