human PFKM shRNA silencing AAV

Cat. No: shAAV-218684

Availability: 4-5 weeks

Name: AAV-h-PFKM-shRNA

This is an AAV expressing shRNA for silencing of Human PFKM.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PFKM
Gene Name: phosphofructokinase, muscle
Gene ID: 5213
Gene Synonyms: ATP-PFK; GSD7; PFK-1; PFK1; PFKA; PFKX; PPP1R122
ORF Size: 2343 bp
RefSeq#: NM_000289
Gene Description: Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
UniGene ID: Hs.75160
HGNC ID: HGNC:8877