human PFKL shRNA silencing AAV

Cat. No: shAAV-218683

Availability: 4-5 weeks

Name: AAV-h-PFKL-shRNA

This is an AAV expressing shRNA for silencing of Human PFKL.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PFKL
Gene Name: phosphofructokinase, liver type
Gene ID: 5211
Gene Synonyms: ATP-PFK; PFK-B; PFK-L
ORF Size: 2484 bp
RefSeq#: NM_002626
Gene Description: Phosphofructokinase (PFK) is a tetrameric enzyme that catalyzes a key step in glycolysis, namely the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. Separate genes encode a muscle subunit (M) and a liver subunit (L). PFK from muscle is a homotetramer of M subunits, PFK from liver is a homotetramer of L-subunits, while PFK from platelets can be composed of any tetrameric combination of M and L subunits. The protein encoded by this gene represents the L subunit. Alternate splicing results in two transcript variants, one of which is a candidate for nonsense-mediated decay (NMD).
UniGene ID: Hs.255093
HGNC ID: HGNC:8876