human PDXP shRNA silencing AAV

Cat. No: shAAV-218568

Availability: 4-5 weeks

Name: AAV-h-PDXP-shRNA

This is an AAV expressing shRNA for silencing of Human PDXP.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PDXP
Gene Name: pyridoxal phosphatase
Gene ID: 57026
Gene Synonyms: CIN; dJ37E16.5; PLP
ORF Size: 891 bp
RefSeq#: NM_020315
Gene Description: Pyridoxal 5-prime-phosphate (PLP) is the active form of vitamin B6 that acts as a coenzyme in maintaining biochemical homeostasis. The preferred degradation route from PLP to 4-pyridoxic acid involves the dephosphorylation of PLP by PDXP (Jang et al., 2003 (PubMed 14522954)).(supplied by OMIM, Mar 2008)
UniGene ID: Hs.632762
HGNC ID: HGNC:30259