human PDK4 shRNA silencing AAV
Category: AAV > shRNA-Silencing
Cat. No: shAAV-218539
Availability:
4-5 weeks
Name:
AAV-h-PDK4-shRNA
This is an AAV expressing shRNA for silencing of Human PDK4.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Recombinant AAV
- AAV-ITR
- AAV2
- AAV Serotype
- Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- PBS/5% Glycerol
Gene Details
- Species
- Human
- Gene Symbol
- PDK4
- Gene Name
- pyruvate dehydrogenase kinase 4
- Gene ID
- 5166
- ORF Size
- 1236 bp
- RefSeq#
- NM_002612
- Gene Description
- PDK4 is a member of the PDK/BCKDK protein kinase family and encodes a mitochondrial protein with a histidine kinase domain. This protein is located in the matrix of the mitrochondria and inhibits the pyruvate dehydrogenase complex by phosphorylating one of its subunits, thereby contributing to the regulation of glucose metabolism. Expression of this gene is regulated by glucocorticoids, retinoic acid and insulin.
- UniGene ID
- Hs.8364
- HGNC ID
- HGNC:8812
Related Products
Product | Cat No. |
---|---|
AAV-h-PDK4 | AAV-218539 |
AAV-m-PDK4 | AAV-268336 |
Ad-h-PDK4 | ADV-218539 |
Ad-m-PDK4 | ADV-268336 |
AAV-m-PDK4-shRNA | shAAV-268336 |
Ad-h-PDK4-shRNA | shADV-218539 |
Ad-m-PDK4-shRNA | shADV-268336 |
Control Products
Product | Cat No. |
---|---|
AAV1-GFP-U6-shRNA | 7040 |
AAV2-GFP-U6-shRNA | 7041 |
AAV5-GFP-U6-shRNA | 7042 |
AAV6-GFP-U6-shRNA | 7043 |
AAV9-GFP-U6-shRNA | 7045 |
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