human PDE10A shRNA silencing AAV

Cat. No: shAAV-218457

Availability: 6-8 weeks

Name: AAV-h-PDE10A-shRNA

This is an AAV expressing shRNA for silencing of Human PDE10A.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PDE10A
Gene Name: phosphodiesterase 10A
Gene ID: 10846
Gene Synonyms: ADSD2; HSPDE10A; IOLOD; LINC00473; PDE10A19
ORF Size: 2340 bp
RefSeq#: NM_006661
Gene Description: PDE10A belongs to the cyclic nucleotide phosphodiesterase family. It plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This protein can hydrolyze both cAMP and cGMP to the corresponding nucleoside 5' monophosphate, but has higher affinity for cAMP, and is more efficient with cAMP as substrate. Alternatively spliced transcript variants have been described for this gene.
UniGene ID: Hs.348762
HGNC ID: HGNC:8772