human PAX2 shRNA silencing AAV

Cat. No: shAAV-218270

Availability: 6-8 weeks

Name: AAV-h-PAX2-shRNA

This is an AAV expressing shRNA for silencing of Human PAX2.

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Knockdown: shRNA screening service available, please inquire about this service or other options.

Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PAX2
Gene Name: paired box 2
Gene ID: 5076
Gene Synonyms: FSGS7; PAPRS
ORF Size: 1296 bp
RefSeq#: NM_000278
Gene Description: PAX2 encodes paired box gene 2, one of many human homologues of the Drosophila melanogaster gene prd. The central feature of this transcription factor gene family is the conserved DNA-binding paired box domain. PAX2 is believed to be a target of transcriptional supression by the tumor supressor gene WT1. Mutations within PAX2 have been shown to result in optic nerve colobomas and renal hypoplasia. Alternative splicing of this gene results in multiple transcript variants.
UniGene ID: Hs.155644
HGNC ID: HGNC:8616