human PARVB shRNA silencing AAV

Cat. No: shAAV-218253

Availability: 4-5 weeks

Name: AAV-h-PARVB-shRNA

This is an AAV expressing shRNA for silencing of Human PARVB.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: PARVB
Gene Name: parvin beta
Gene ID: 29780
Gene Synonyms: CGI-56
ORF Size: 1095 bp
RefSeq#: NM_013327
Gene Description: PARVB encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants.
UniGene ID: Hs.475074
HGNC ID: HGNC:14653