human ORC4L shRNA silencing AAV

Cat. No: shAAV-217927

Availability: 4-5 weeks

Name: AAV-h-ORC4L-shRNA

This is an AAV expressing shRNA for silencing of Human ORC4.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: ORC4
Gene Name: origin recognition complex subunit 4
Gene ID: 5000
Gene Synonyms: ORC4L; ORC4P
ORF Size: 1311 bp
RefSeq#: NM_002552
Gene Description: The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.
UniGene ID: Hs.558364
HGNC ID: HGNC:8490