human OGT shRNA silencing AAV

Cat. No: shAAV-217390

Availability: 4-5 weeks

Name: AAV-h-OGT-shRNA

This is an AAV expressing shRNA for silencing of Human OGT.

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Viral Backbone: Recombinant AAV
AAV-ITR: AAV2
AAV Serotype: Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
Promoter: U6
Reporter: eGFP (default), optional CFP, YFP, RFP, mCherry
Storage Buffer: PBS/5% Glycerol

Species: Human
Gene Symbol: OGT
Gene Name: O-linked N-acetylglucosamine (GlcNAc) transferase
Gene ID: 8473
Gene Synonyms: HINCUT-1; HRNT1; O-GLCNAC
ORF Size: 3111 bp
RefSeq#: NM_181672
Gene Description: OGT encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
UniGene ID: Hs.405410
HGNC ID: HGNC:8127